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SaintyCo pharmaceutical mixer is high-tech and flexible accessories designed to move in different axes and angles. These include SaintyCo single arm mixer, SaintyCo multi-directional motions mixer and SaintyCo souage-cone mixing machine.
The mixers have simple and compact designs consisting of three main parts – supporting shelf, control and driving system. To attain good mixing co-efficient, SaintyCo pharmaceutical mixers have fully automated systems where users configure mixing time and speed.
Mixer motors are connected to allow for a 3D space motion, with a high degree of precision. Such motions enhance faster material flow and diffusion since they reduce gravity segregation.
To ensure a safe operation, the SaintyCo mixers do not have dead angles, concave-convex face and screws on their surfaces. The roughness of its inner section is Ra≤0.2m, while the outer section is Ra ≤0.4m.
Other special equipment such as the V-mixer, robbin mixer and sigma mixers can mix granules and dried powders. The mixers can attain a 360 °C of rotation resulting in a uniform mixing.
All SaintyCo pharmaceutical mixers have airtight silicon latex seals to prevent spilling of content during mixing. SaintyCo pharmaceutical mixers are suitable for a wide range of applications such in pharmaceutical, material processing, raw medicine processing foodstuff and chemical industries.
Key Features of SaintyCo Pharmaceutical Mixer
- Efficient and faster mixing speed
- cGMP and CE compliant
- Cos competitive
- Mixing coefficient is 99%
- Charging coefficient ranges between 50% and 80%
Pharmaceutical Mixer: The Ultimate FAQ Guide
Today’s guide will walk you through the vital aspects of pharmaceutical mixers.
You will find answers to all the questions you could be having about pharmaceutical mixing equipment.
Whether you want to learn about ribbon mixers or drum mixers – they are all here:
- What is Pharmaceutical Mixer?
- Which Types of Pharmaceutical Mixer Machine are there?
- How does Pharmaceutical Mixer compare to Pharmaceutical Blender
- What are the Benefits of Pharmaceutical Mixer?
- Which Material can you process in Pharmaceutical Mixer?
- Are there Specific Features to Look for when Importing Pharmaceutical Mixer
- What is Pharmaceutical Mixer used for?
- Is Pharmaceutical Mixer same as Pharmaceutical Bin Blender?
- What is the best Material for Pharmaceutical Mixer?
- Which Industries use Pharmaceutical Mixer?
- What is Multi-directional Motion Mixer?
- What is the Working Principle for Pharmaceutical Mixer?
- Are there Limitations of Pharmaceutical Mixer?
- Which Factors affect the Efficiency of Pharmaceutical Mixer?
- Are there Specific Quality Standards for Pharmaceutical Mixer?
- Does Pharmaceutical Mixer has Maximum Degree of Roughness?
- How does Ribbon Mixer compare to V Mixer?
- How can you Charge and Discharge Material from the Pharmaceutical Mixer?
- Is Pharmaceutical Homogenizer same as Pharmaceutical Mixers?
- How does Double Cone Blender compare to Octagonal Blender?
- How many Mixing Mechanisms exist in Pharmaceutical Industry?
- How does Pharmaceutical Drum Mixer compare to Pharmaceutical Bin Mixer?
What is Pharmaceutical Mixer?
Pharmaceutical mixers are used in mixing pharmaceutical products.
The products mixed can be in the form of powder, granular, and some instances, liquid.
The mixer helps in mixing products that would otherwise not nix easily.
When mixing the products, the machine breakdown the composition of the molecules resulting in a harmonized mixture.
Which Types of Pharmaceutical Mixer Machine are there?
In recent times, a variety of pharmaceutical mixers have been invented. The machines differ in terms of the kind of substances that they can mix.
Some of these machines are discussed below:
1. Agitator
This pharmaceutical mixer is relied on when mixing liquids.
It is recommended that when using this machine, the liquids being mixed should not be highly viscous.
The agitator is also relied on in mixing gases into liquid products.
You can also rely on this mixer when mixing liquids that cannot easily mix.
Agitator mixer
2. Ribbon Blender
In the pharmaceutical industry, there are instances that you will be mixing heavy solids.
Ribbon blender becomes the ultimate solution in such cases.
The machine has a cylinder and a ribbon-like paddle that keeps rotating around a central axis.
This makes it the best pharmaceutical mixer when handling pharmaceutical powders.
3. Paddle Mixer
The characteristics of the mixer are akin to those of the ribbon blender, save for a few differences.
The mixer’s blades are paddle-shaped and obtrude from the axis.
This is similar to how sheer ribbons protrude from the axis in the case of ribbon blenders.
In terms of mixing, this machine efficiently mixes dry and friable products.
You can also rely on it to mix both dry and wet products.
The machine also mixes viscous pharmaceutical products giving it an edge over other pharmaceutical mixers.
Paddle mixer machine
4. Static Mixers
The distinctive feature of this machine is that all its parts are static.
The design heavily relies on obstructions.
The obstructions are in the form of ribbons.
It is through these ribbons that the liquids flow.
The moment you let liquid pharmaceutical products flow into the cylinder, the obstruction slows down the flow.
This results in slow but effective and even mixing.
This results in a homogeneous liquid.
To your advantage, this does not require power; as such, you will have cut down production costs.
You won’t also have to service the machine since all parts of the machine are immobile.
This is a very cost-effective measure of production.
Static mixer
5. Emulsifiers
This is the most reliable machine in mixing immiscible liquids.
Take, for instance, when you intend to mix water and oil, this will be the most relevant machine.
Emulsifier mixer approaches this by first applying pressure on the immiscible liquids.
From this point, the liquids have to pass through tiny filters.
When this happens, the large molecules are broken down, making it easy for the two immiscible liquids to mix uniformly.
In the food industry, emulsifiers are relied on in mixing cream with milk.
The cream’s molecules are larger in comparison to milk.
Using the same procedure, cream molecules are broken down as they pass through tiny filters.
In different industries, this process is often hastened by the use of emulsifying agents.
Emulsifier mixer
6. Homogenizers
This is also another pharmaceutical mixer that relies on pressure to mix two liquids.
The great force and pressure involved translate into a uniformly mixed liquid.
The distinctive feature of this machine is that it has erected shearing blades.
The blades turn at very high speed within the container.
Homogenizer mixer
7. Drum Mixer
There is a variety of mixers in this category. Some of these machines are portable, while others are not portable.
These machines are relied on in the pharmaceutical industry to mix medium and low viscous products.
Syrups are some of the products can that can be effectively mixed using this machine.
In the cosmetics industry, drum mixers can be used in mixing body creams and lotions.
8. Heavy-duty Mixers
Planetary mixers fall under this category.
The same applies to multi-shaft mixers.
If your industry mixes viscous products, then these are the most reliable machines.
These machines have the capability of mixing products with a viscosity of 750,000 centipoises.
High shear mixer
9. Tumble Blender
This is the most reliable machine in mixing powders, solid products, and liquids.
It is the tumbling the products keep moving.
The force of gravity generated during this operation results in the effective breaking and mixing of the materials.
Tumble blender
How does Pharmaceutical Mixer compare to Pharmaceutical Blender
Pharmaceutical blenders and mixers perform the same functions.
The ideal purpose is to create homogeneous blends from different materials.
There are, however, variations in terms of consistency and temperatures at which these machines operate.
What are the Benefits of Pharmaceutical Mixer?
Pharmaceutical mixers come with several advantages for you as a manufacturer.
Some of these advantages include:
Multi directional mixer
· Upholding Hygienic Standards
Cleanliness and sanitation are essential concerns in the production of pharmaceutical products.
Pharmaceutical mixers are not only air driven but also electric.
This minimizes contamination occasioned by grease leaks.
Further, it also ensures that there is little contact between the product and the employees involved in the process.
As a result, instances of contamination are minimized.
· Thorough Mixing
All pharmaceutical products have to be mixed thoroughly before the production process begins.
You don’t want to be sued for the wrong composition of the pharmaceutical products you have manufactured.
This can only be prevented by using quality pharmaceutical mixers.
Mixers ensure thorough mixing resulting in homogeneous products.
· Efficiency
Pharmaceutical machines are also a reliable strategy for improving efficiency in the pharmaceutical industry.
Apart from increasing production, these machines are also a time-saving strategy.
This can significantly impact profitability.
· Mixing of Immiscible Liquids
Pharmaceutical mixers can also be relied on in mixing immiscible liquids.
In the pharmaceutical industry, there are instances in which water is mixed with liquid.
In the food industry, this is beneficial in mixing cream and milk.
· Environmental Conservation
Pharmaceutical mixers usually minimize the production of dust during the manufacturing process.
Gases emitted during mixing can be hazardous to the environment.
However, pharmaceutical mixers contain the emission of such gases.
· Reduces Reliance on Human Labor
In production, human labor is one of the most expensive variables.
However, with pharmaceutical machines, this cost is minimized.
Another challenge associated with human labor is unreliable outcomes due to fatigue.
There is also a higher chance of contamination when relying on human labor.
All these challenges can be addressed by the use of pharmaceutical mixers.
Which Material can you process in Pharmaceutical Mixer?
Pharmaceutical mixers can be relied on in processing various materials.
Some of the elements that are mixed include granules, powder, and liquid.
The processes through which these materials are mixed include emulsification and blending.
This is achieved by breaking down large molecules into smaller ones.
Are there Specific Features to Look for when Importing Pharmaceutical Mixer
Just like any other machine, there are several features to look out for when purchasing a pharmaceutical mixer.
Below are some of the considerations you should make.
Single arm pharmaceutical mixer
1. Efficiency
It is essential to ensure that the pharmaceutical mixer you are importing is efficient.
Some of the factors that influence effectiveness include operational speed and precision.
It would help if you also considered the loss-minimizing mechanism of the machine during the mixing process.
It is also essential to assess power consumption.
If from your assessment, the considerations are adequately addressed, then this is a good machine.
2. User Safety
This is also an essential consideration when purchasing a pharmaceutical machine.
Your employees have to be safe when using the machine.
This will save you compensation costs occasioned by injuries sustained by the machine’s operators.
The following considerations should be made during this process.
First, ensure that the rotating parts are securely fastened.
This usually averts instances of cylinder falloffs.
If this is not prevented, then you are likely to record fatalities.
Ensure that the machine has sensors that will detect and stop it from operating in case of an operational hitch.
You most probably want to save your machine from power surges and electrical faults.
An electric cut out will help you prevent such ugly incidences.
It is advisable to purchase a pharmaceutical mixer with isolated moving parts.
This will effectively help inhibit the operator from accessing the essential and potentially dangerous parts.
These parts include the motor shaft and gears.
Check out if the machine has an auto-lock system.
The cylinder should always be locked during the mixing process.
With the automation, this will be easier for the operator to handle.
Lastly, ensure that the machine does not have sharp edges or exposed screws.
Such features can always cause injuries to the operator.
You don’t want to miss out on production because a protruding screw injured your operators.
3. Environmentally Friendly
Sound can be very destructive for other employees whose job does not entail operating the pharmaceutical mixer.
Ensure that the machine you import produces less noise.
For purposes of environmental conservation, ensure the machine produces minimal dust during the production.
4. Durability
You should ensure that the mixer you are importing is durable.
You can ascertain this fact by checking out of the quality of materials used in its manufacturing.
FDA approves of the use of stainless steel in manufacturing pharmaceutical mixers.
Another way to ascertain whether the machine is durable is through checking reviews on the website.
This will give you a glimpse of the customer experience with the mixer.
5. cGMP Compliance
This refers to current good manufacturing practices.
This is one of the essential quality certifications to look out for when purchasing a pharmaceutical mixer.
6. Ability to Mix Different Products
You don’t want to purchase the same machine twice simply because you are processing products with different chemical compositions.
A good mixer should be able to mix products with this varying chemical composition.
7. Dependable Electrical Controls
The mixer you are importing should have controllable electrical control features.
The control system should also be user-friendly.
In case of a breakdown, the mixer should be easy to maintain.
8. Friendly User-interface
The user interface should be easily understandable and guarantee the total operator control when the machine is in use.
Some of the operations that should be easily controlled from the user interface include the mixing time and speed.
9. Flexibility
The pharmaceutical mixer should have a flexible design.
This helps in ensuring that as the user you have an increased mixing capability.
What is Pharmaceutical Mixer used for?
Pharmaceutical mixing machine
Just be the name mixer, these machines’ use is a little obvious.
They are relied on in mixing different pharmaceutical substances into homogeneous products.
However, there is more than meets the eye in these procedures.
Pharmaceutical mixers can be used to suspend solid substances in liquid substances in industrial production.
Some explain the manufacturing process for pharmaceutical suspensions.
For immiscible pharmaceutical products, pharmaceutical mixers are relied on for the emulsification process.
This helps in ensuring that immiscible pharmaceutical products are homogeneously mixed.
Thirdly, you can rely on pharmaceutical mixers to dissolve powders, polymers, and granules into a liquid.
This is equally an essential step in manufacturing pharmaceuticals.
Is Pharmaceutical Mixer same as Pharmaceutical Bin Blender?
Bin blender
Although both pharmaceutical mixers and bin blenders perform the same function, there is a slight difference.
Bin blenders are mainly used in mixing dry powders used in the manufacture of both capsules and tablets.
However, pharmaceutical mixers is a more general term.
It refers to mixers relied on mixing virtually all pharmaceutical products regardless of the form they are in.
Pharmaceutical mixers can mix granules, powders, and liquids.
What is the best Material for Pharmaceutical Mixer?
The manufacture of pharmaceutical blenders is based on two main products.
These include stainless steel and carbon steel.
Carbon steel is used in making the rotary body.
It is preferred for its rust-resistant attribute.
Stainless steel, on the other hand, is used in making the contact parts.
Which Industries use Pharmaceutical Mixer?
Powder
Several industries rely on pharmaceutical mixers.
Some of these industries are discussed hereby.
Adhesive and sealant industry is one of the sectors that rely on pharmaceutical mixers.
Just like in the pharmaceutical industry, they use it in mixing products.
The agricultural sector also relies on pharmaceutical mixers.
Agrochemical industries, for example, rely on use mixers in mixing animal nutrition.
They also rely on the mixer when developing veterinary drugs and anti-pesticides.
Sewerage companies also rely on mixers.
For this industry, the machine is used in purifying dirty water.
Another industry that relies on pharmaceutical mixers is the oil and gas industry.
Mixers are used in mixing various petroleum products to create a new product.
In the cosmetic industries, pharmaceutical mixers are used in mixing various beauty products.
These include creams, gels, moisteners, and shampoos.
Chemical industries, on the other hand, rely on mixers to mix different chemicals.
This is done to ensure that these chemicals meet the desired composition and efficiency when they are finally sold.
Paint industries also rely on mixers.
This helps improve the quality of the paints and coatings.
This also applies to inks.
In the food and beverage industries, there is an overreliance on the mixing machines.
You have most probably seen mixed nuts or even juices.
These cannot be on retail shelves without the use of a mixer.
So essential is the machine in the industry that it won’t be possible to produce creamed milk without emulsification by mixing machine.
Most importantly, mixers are used in the pharmaceutical industry.
They are relied on in manufacturing oral suspensions and saline solutions.
Additionally, pharmaceutical mixers are relied on in manufacturing therapy creams and lotions.
What is Multi-directional Motion Mixer?
Multi directional mixer
Multi-directional motion mixers usually have a drum that moves in the opposite direction during mixing.
With this kind of motion, the mixed materials
The movement makes the already mixed materials to drift from one end of the machine to the other.
Further, the drum usually moves randomly, resulting in thorough and even mixing of all the materials being processed.
It is for this reason that a multi-directional motion mixer has become popular as the product cannot de-mix.
The surface of the machine is smooth, and as such, efficiency is achieved in the mixing process.
Another advantage it enjoys over other mixers is that it can be easily cleaned.
This hygienic feature minimizes product contamination during the manufacturing process.
The machine also operates while closed.
This means that it is environmentally friendly.
What is the Working Principle for Pharmaceutical Mixer?
The first step involves filling the mixer half-way its volume.
This is a necessary step in ensuring that it operates efficiently.
Secondly, you should set both time and speed before turning on the power switch for the machine to run.
With the necessary setting done and power switched on, the container moves in one direction as the ribbons move in another.
For the powder to mix well, the cylinder and ribbon paddles rotate on the central axis.
This results in a uniformly and evenly mixed powder.
On mixing the materials, they are discharged off the system.
Are there Limitations of Pharmaceutical Mixer?
When it comes to limitations, the pharmaceutical mixer machines’ case is not exceptional.
It equally has disadvantages.
Below is a discussion of some of the challenges you will most probably experience when using these machines.
· Investment Costs
Just like any other pharmaceutical machine, the initial cost involved in acquiring a pharmaceutical mixer is high.
Although there are variations in prices depending on the products that one tends to process, these machines are costly.
Installation costs are also bound to set you back more financially.
After installation, you are also bound to incur maintenance and power costs.
Additionally, you will have to hire an operator.
This also comes with further financial obligations.
· Small Loading Ratio
Most pharmaceutical mixers have small capacities.
As a result, they have a very small loading ratio.
With the operational costs involved, this can be a very long and tedious process for a company aiming at large output.
Which Factors affect the Efficiency of Pharmaceutical Mixer?
Ribbon mixer
· Physical Properties of Products
Pharmaceutical mixers usually mix various products.
Some of the physical variations in these products include stickiness and distribution.
It can also be wettability or density.
These physical properties dictate how efficient a mixer will operate.
· Particles
When mixing products with different sizes of particles, they are likely to separate.
Smaller particles will come in-between the large particles.
For particles to mix freely, they should have a homogeneous size.
This also applies to shape.
When the particles are spherical, they are likely to mix well compared to when they are in a different shape.
Equally, particle charge will also dictate levels of efficiency.
When particles have attractive force, mixing might not happen as expected.
· Quality of Mixing Machine
For purposes of efficiency, it is important that you purchase a high-quality mixing machine.
The machine should be efficient and affordable.
The machine should also be dependable.
Are there Specific Quality Standards for Pharmaceutical Mixer?
You don’t just want to purchase a pharmaceutical mixer haphazardly without confirming its quality.
There are various quality standards to consider when shopping for these machines.
Multiple regulatory bodies develop these standards.
Look out for the qualities discussed below.
· cGMP
This is one of the most common standardization marks in the pharmaceutical industry.
It refers to current good manufacturing practices.
These standards are set by the Food and Drug Administration (FDA).
A pharmaceutical machine bearing this mark will most definitely serve you efficiently.
· C.E.
E is a European Economic Area standardization.
For a product to bear this mark, it will have conformed to safety, environmental, and health standards.
You must check this mark out when window-shopping your pharmaceutical mixer from the European market.
Pharmaceutical machines manufactured outside Europe but manufactured within its market should also bear this mark.
· RoHS
The term refers to the Restriction of Hazardous Substances.
This standardization mark is also used in the European market.
It protects you as a consumer of the pharmaceutical mixer by restricting several products.
It restricts lead, chromium and mercury and cadmium.
· CCC
This standardization mark is usually used on Chinese products.
Chine is today awash by domestic companies and satellite industries that have to be regulated.
If you are sourcing your pharmaceutical mixer from China, then you ought to look out for this mark.
· ISO
This could pass to be one of the most common standards in the world.
It is consumer-centered.
You will have to check it out before making a purchase.
Does Pharmaceutical Mixer has Maximum Degree of Roughness?
Yes.
Quality polish is usually used in both the internal and external surfaces of a pharmaceutical mixer.
For the inner surface, the tolerable roughness degree is Ra≤0.2μm, while the external surface’s is Ra≤0.4μm.
How does Ribbon Mixer compare to V Mixer?
V mixer
Ribbon mixing machine
Ribbon mixers have a different operating system compared to v-mixers.
For they also differ in terms of design.
For the ribbon mixer, the ribbons are in the middle and the outer part.
Its containers also tend to move in opposite directions.
This results in the rotation of the paddles on the central axis.
As a result, the materials are evenly mixed.
For the v-mixer, this is somehow different.
The v-mixer mixes the products as its container rotates on the pivot.
As the rotation continues, the product breaks and gets evenly mixed.
How can you Charge and Discharge Material from the Pharmaceutical Mixer?
For charging, this is done manually in the mixing tank.
For discharge, this can only be done manually after the mixing has been done.
However, most pharmaceutical mixer machines today are automated.
This means that both functions are performed automatically.
Is Pharmaceutical Homogenizer same as Pharmaceutical Mixers?
This is another type of pharmaceutical mixer.
Unlike your regular pharmaceutical machine that mixes different products, this mixer has an added advantage.
It can be relied on in reducing the particles to smaller sizes to enhance mixing.
As such, you can rely on it in scaling mixed drugs.
This makes scaling procedures affordable.
You can also rely on homogenizers if your company produces molecules, including emulsions.
You can also depend it on the dispersion of the products.
How does Double Cone Blender compare to Octagonal Blender?
Double cone blender
Octagonal blender
Both double cone and octagonal blenders’ designs have to comply with the current excellent manufacturing practice standards.
Both machines are used in mixing granular products.
The bottom line is that they don’t depend on high shearing force.
Both machines are reliable and quick in mixing.
They are also safe and mix products with precision.
This can be attributed to the fact that they tend to charge faster and discharge the ports in a similar manner.
Maintaining the hygienic standards of the machines is very easy.
This also applies to their maintenance.
Before the products are processed, they are charged, and the containers are locked.
This applies to both the blenders.
Both mixers are manufactured from stainless steel. While the internal parts are made from AISI 316, the external components are manufactured from AISI 304.
In terms of control, both machines rely on electric control panels.
How many Mixing Mechanisms exist in Pharmaceutical Industry?
Usually, the mechanism for mixing depends on the form of substances that a pharmaceutical mixer handles.
Some of these dosages include liquids, solids, and semi-solids.
i. Solid Mixing
This mixing mechanism is affected by the physical properties of the solid products undergoing the mixing procedure.
Some of these physical features include shapes of the particles, the size of the particles, wettability, and stickiness.
Density is also another physical feature.
ii. Mixing of Liquids
Liquids are usually mixed in two stages.
You can apply shear to the particles in a process known as localized mixing.
In the process, all particles are taken through a shearing zone, also known as a general movement.
This mechanism helps in ensuring that a final uniform mixture is formed.
Four main mechanisms are used for mixing liquids.
These include turbulent flow, molecular diffusion, and bulk transport.
They also rely on turbulent flow.
iii. Semi-solid Mixing
In this case, the mechanism used is determined by the characteristics of the products.
Although the mixture formed can yield sedimentation, it is homogenous, and you might not be able to segregate its composition.
Various machines are used in this process.
They include a sigma blade mixer and planetary mixer.
Alternatively, you can use triple-roller mill
How does Pharmaceutical Drum Mixer compare to Pharmaceutical Bin Mixer?
You can use your pharmaceutical bin with other pharmaceutical equipment.
This is because the bin can carry pharmaceutical products and subsequently ensure smooth flow.
The flow occurs as earlier predetermined.
Pharmaceutical bin mixers are relied on in achieving a smooth blend.
This results in a harmonized mixing.
However, both pharmaceutical drum mixers and pharmaceutical bin blenders are relied on in environmental conservation.
When one uses these machines, there is a surety that gas emissions are controlled.
This can be attributed to the fact that they operate while closed.
For purposes of hygiene, both the machines are fabricated using stainless steel.
Apart from sanitation, stainless steel is also relied on because of its anti-rust feature.
Most importantly, stainless steel is easier to maintain and prevents contamination.
Both pharmaceutical drum mixers and pharmaceutical bin blenders are used in the pharmaceutical industry.
They help mix various ingredients used in manufacturing medical drugs.
As such, these machines are a solution to inefficiency in the pharmaceutical industry occasioned by reliance on human labor.
Both pharmaceutical drum mixers and pharmaceutical bin blenders are subject to international standards.
One of the leading quality standards in the pharmaceutical industry that these machines have to attain is CGMP.
This refers to current good manufacturing practices.
The machines also have to achieve ISO certification to be accepted in the market.
With this information, you can easily choose a pharmaceutical mixer for your applications.
At SaintyCo, we offer a range of pharmaceutical mixers depending on your needs and requirements.